Wednesday, 17 January 2018
Peria Katak (Momordica Charantia)
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Momordica charantia is from the Cucurbitaceae family, a slender- stemmed tendril climber, bearing mildly bitter fruits (known as Bitter Gourd) with slender tips at both ends. The fruit is widely used for various ailments such as diabetes, hypertension, diarrhea, and stomach ache.

Numerous studies have documented the anti-diabetic properties of Momordica charantia.1,2  A study has also demonstrated its ability to inhibit activity against guanylate cyclase, an enzyme involved in the development of psoriasis, leukemia and cancers. 3  A phytochemical isolated from M. charantia, momordin, was shown to have a potential activity against CD5 positive leukemia and lymphomas in vivo.4

References:

  1. Ali L, Khan AK, Mamun MI, et al. Studies on hypoglycemic effects of fruit pulp, seed and whole plant of Momordica charantia on normal and diabetic model rats. Planta Med. 1993;59(5):408-12.
  2. Miura T, Itoh C, Iwamoto N, et al. Hypoglycemic activity of the fruit of the Momordica charantia in type 2 diabetic mice. J Nutr Sci Vitaminol. 2001;47(5):340-44.
  3. Vesely DL, Graves WR, Lo TM, Fletcher MA, Levey GS. Isolation of a guanylate cyclase inhibitor from the balsam pear (Momordica charantia abbreviata). Biochem Biophys Res Commun. 1997;77(4):1294-99.
  4. Bologngnesi PG, Caretto P, et al. In vitro and in vivo properties of an anti CD 5-momordin immunotoxin on normal and neoplastic T lymphocytes. Cancer Immuonol Immunotherapy. 1993;36(5):346-350.
 

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